Estimation of the Ratio between Copper & Zinc in Pregnant Women Suffering from Iron Deficiency Anemia

Anemia is one of the pathological conditions that have multiple and varied causes, including what is known as iron deficiency, especially in women and during pregnancy, where the condition is known as “iron deficiency anemia”. One of the objectives of this research is to investigate and study the clinical significance of iron and other elements known as “minor elements” in the blood such as copper, zinc, and the possible relationship of these elements to this type of anemia. The results of this research showed an increase in the level of copper in the blood serum of pregnant women with iron deficiency anemia in all stages of pregnancy, especially in the third stage, compared to the corresponding stages in normal pregnancy, as well as an increase in the level of copper in the blood of healthy pregnant women compared to the healthy group of non-pregnant women. The study also showed a decrease in the level of zinc in the serum of the pregnant mother with iron deficiency anemia in all stages of pregnancy, especially in the third stage, where it was a significant decrease (probability <0.001) compared with the corresponding stages in normal pregnancy. A significant decrease in the level of zinc was also observed in the serum of healthy pregnant women (probability <0.001) compared with that of non-pregnant healthy women. Low levels of both hemoglobin and the volume of pressurized blood cells were recorded, and this decrease increases with the aging of pregnancy in pregnant women with iron deficiency anemia, especially in the second stage, where it becomes a significant decrease (probability <0.001) compared to healthy non-pregnant women. This significant decrease was also recorded in healthy pregnant women (P<0.001) compared to non-pregnant healthy women. The ratio of copper to zinc increased in its results in the healthy pregnant mother and in all stages of pregnancy compared to the non-pregnant woman. This percentage also increased in the pregnant mother suffering from iron deficiency anemia in the three stages of pregnancy compared to the corresponding stages in the normal pregnancy. In the second stage of normal pregnancy, the results of the study showed a positive significant relationship between the level of hemoglobin and the level of zinc, probability (0.001), while there was a negative significant relationship with the level of copper (probability <0.001). In general, the results of this research show that the level of copper and zinc and the ratio between them that has been studied is affected (increase or decrease) by the condition of iron deficiency anemia in pregnant women. The results of measuring the levels of these elements in addition to ratio between the copper and zinc can be used as additional laboratory tests to assess the anemia caused by iron deficiency in women during the period of time Pregnancy. The ratio of both elements should be optimized in pregnancy, to improve reproduction results and reduce the chance of spontaneous abortion.

Anahtar Kelimeler: Copper & Zinc, Pregnant Women, Iron Deficiency Anemia

Anemia is one of the pathological conditions that have multiple and varied causes, including what is known as iron deficiency, especially in women and during pregnancy, where the condition is known as “iron deficiency anemia”. One of the objectives of this research is to investigate and study the clinical significance of iron and other elements known as “minor elements” in the blood such as copper, zinc, and the possible relationship of these elements to this type of anemia. The results of this research showed an increase in the level of copper in the blood serum of pregnant women with iron deficiency anemia in all stages of pregnancy, especially in the third stage, compared to the corresponding stages in normal pregnancy, as well as an increase in the level of copper in the blood of healthy pregnant women compared to the healthy group of non-pregnant women. The study also showed a decrease in the level of zinc in the serum of the pregnant mother with iron deficiency anemia in all stages of pregnancy, especially in the third stage, where it was a significant decrease (probability <0.001) compared with the corresponding stages in normal pregnancy. A significant decrease in the level of zinc was also observed in the serum of healthy pregnant women (probability <0.001) compared with that of non-pregnant healthy women. Low levels of both hemoglobin and the volume of pressurized blood cells were recorded, and this decrease increases with the aging of pregnancy in pregnant women with iron deficiency anemia, especially in the second stage, where it becomes a significant decrease (probability <0.001) compared to healthy non-pregnant women. This significant decrease was also recorded in healthy pregnant women (P<0.001) compared to non-pregnant healthy women. The ratio of copper to zinc increased in its results in the healthy pregnant mother and in all stages of pregnancy compared to the non-pregnant woman. This percentage also increased in the pregnant mother suffering from iron deficiency anemia in the three stages of pregnancy compared to the corresponding stages in the normal pregnancy. In the second stage of normal pregnancy, the results of the study showed a positive significant relationship between the level of hemoglobin and the level of zinc, probability (0.001), while there was a negative significant relationship with the level of copper (probability <0.001). In general, the results of this research show that the level of copper and zinc and the ratio between them that has been studied is affected (increase or decrease) by the condition of iron deficiency anemia in pregnant women. The results of measuring the levels of these elements in addition to ratio between the copper and zinc can be used as additional laboratory tests to assess the anemia caused by iron deficiency in women during the period of time Pregnancy. The ratio of both elements should be optimized in pregnancy, to improve reproduction results and reduce the chance of spontaneous abortion.

Keywords: Copper & Zinc, Pregnant Women, Iron Deficiency Anemia

Al Sabaiwy, K. A. M., Al-Qattan, M. A. A. & Al-Haidari, M. (2022). Estimation of the Ratio between Copper & Zinc in Pregnant Women Suffering from Iron Deficiency Anemia. Journal of Current Researches on Health Sector, 12 (2), 139-176.